The Institute of Human Genetics (IHG) began in 1990 as the Medical Genetics Unit of the University of the Philippines College of Medicine which in 1999 became as one of the service and research oriented institutes of the National Institutes of Health-University of the Philippines Manila (NIH-UP). Since then all services of the Medical Genetics Unit were transferred to the Institute and is now the largest provider of genetic services in the country.


Oral Cleft

Oral clefts are among the most common congenital anomalies. Various literature estimate global incidence of oral clefts at 1 every 500-1000 live births, which varies with race and gender. Asians in particular, are at a higher risk for oral clefts. The prevalence of oral cleft (cleft lip with or without cleft palate) in the Philippines was reported in 1997 as 2 per 1000 livebirths. Representatives from the IHG-NIH-UP, the Philippine Association of Plastic, Reconstructive and Aesthetic Surgeons Inc. (PAPRAS); the Philippine Society of Otolaryngology - Head and Neck Surgery (PSO-HNS); Operation Smile Philippines Foundation Inc. (OSPF); and the Philippine Band of Mercy (PBM) established the Philippine Oral Cleft Study Group (POCSG) to implement a registry program for patients with oral clefts (cleft lip and/or palate) in the Philippines. Specifically, the POCSG aims to determine the incidence of oral clefts, the different types of oral clefts and identify possible risk factors for oral clefts in the country. The registry also collects data on maternal history and demographic profile to better understand oral cleft occurrences. The POCSG aims to cover all identified cases of oral clefts in the country.

From May 2003- December 2006, The Philippine Oral Cleft Registry has been able to register 2,324 cases all over the country.