The Institute of Human Genetics (IHG) began in 1990 as the Medical Genetics Unit of the University of the Philippines College of Medicine which in 1999 became as one of the service and research oriented institutes of the National Institutes of Health-University of the Philippines Manila (NIH-UP). Since then all services of the Medical Genetics Unit were transferred to the Institute and is now the largest provider of genetic services in the country.


Cardiovascular Genetics

In the Philippines, cardiovascular diseases are the leading cause of mortality, and rank among the top ten causes of morbidity for both genders. This trend is especially alarming since these diseases are considered to be preventable and therefore complications arising from these should be avoidable.

The study group made up of cardiologists and geneticists explores the genetic basis of common but complex types of diseases particularly, cardiovascular disease prevalent among Filipinos. Investigations are underway on how this knowledge can be used to promote disease prevention and improve health care. The group has internationally published articles on LDL-R gene mutations in Filipino families with Familial Hypercholesterolemia and polymorphisms in the Cholesteryl Ester Transfer Protein (CETP) gene and its association with cardiovascular disease among Filipinos.